Designed multiple ligands. An emerging drug discovery paradigm.

Angiotensin-Converting Enzyme Inhibitors/chemistry,pharmacology Animals Anti-Allergic Agents/chemistry,pharmacology Anti-Inflammatory Agents, Non-Steroidal/chemistry,pharmacology Antidepressive Agents/chemistry,pharmacology Antihypertensive Agents/chemistry,pharmacology Antipsychotic Agents/chemistry,pharmacology Chemistry, Pharmaceutical/trends Dopamine D2 Receptor Antagonists Drug Design Humans Ligands Metabolic Diseases/drug therapy Peroxisome Proliferator-Activated Receptors/drug effects Receptors, Histamine H1/drug effects Serotonin Uptake Inhibitors/chemistry,pharmacology

Angiotensin-Converting Enzyme Inhibitors Anti-Allergic Agents Anti-Inflammatory Agents, Non-Steroidal Antidepressive Agents Antihypertensive Agents Antipsychotic Agents Dopamine D2 Receptor Antagonists Ligands Peroxisome Proliferator-Activated Receptors Receptors, Histamine H1 Serotonin Uptake Inhibitors