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PMID: 16217816 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Accumulation of an E,E,E-triene by the monensin-producing polyketide synthase when oxidative cyclization is blocked.

Angewandte Chemie (International ed. in English) ·Vol. 44 ·No. 43 ·2005-11-04 ·Pages 7075-8

Bhatt A, Stark CB, Harvey BM, Gallimore AR, Demydchuk YA, Spencer JB, Staunton J, Leadlay PF

Abstract

暂无摘要

MeSH Terms

Cyclization Molecular Conformation Monensin/analogs & derivatives,biosynthesis,chemistry Oxidation-Reduction Polyenes/chemistry Polyketide Synthases/chemistry Stereoisomerism Streptomyces/enzymology,genetics

Chemicals

Polyenes Polyketide Synthases Monensin

Authors & Affiliations

8 authors, click to expand affiliations / ORCID

Bhatt Apoorva

Department of Biochemistry, University of Cambridge, UK.

Stark Christian B W

Harvey Barbara M

Gallimore Andrew R

Demydchuk Yuliya A

Spencer Jonathan B

Staunton James

Leadlay Peter F

Article Info

Journal

Angewandte Chemie (International ed. in English)

Abbr.

Angew Chem Int Ed Engl

ISSN

1433-7851

DOI

10.1002/anie.200501757

Published

2005-11-04

Pages

7075-8

Language

English

Region

Germany

NLM ID

0370543

Subset

External Links

PubMed source DOI: 10.1002/anie.200501757 View journal details

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Accumulation of an E,E,E-triene by the monensin-producing polyketide synthase when oxidative cyclization is blocked.

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