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PMID: 16169926 Published · ppublish English Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Galaxy: a platform for interactive large-scale genome analysis.

Genome research ·Vol. 15 ·No. 10 ·2005-10-00 ·Pages 1451-5

Giardine B, Riemer C, Hardison RC, Burhans R, Elnitski L, Shah P, Zhang Y, Blankenberg D, Albert I, Taylor J, Miller W, Kent WJ, Nekrutenko A

Abstract

Accessing and analyzing the exponentially expanding genomic sequence and functional data pose a challenge for biomedical researchers. Here we describe an interactive system, Galaxy, that combines the power of existing genome annotation databases with a simple Web portal to enable users to search remote resources, combine data from independent queries, and visualize the results. The heart of Galaxy is a flexible history system that stores the queries from each user; performs operations such as intersections, unions, and subtractions; and links to other computational tools. Galaxy can be accessed at http://g2.bx.psu.edu.

MeSH Terms
Biological Evolution Databases, Genetic Genome Internet Promoter Regions, Genetic
Authors & Affiliations
13 authors, click to expand affiliations / ORCID
Giardine Belinda
Center for Comparative Genomics and Bioinformatics, Huck Institutes for Life Sciences, Penn State University, University Park, Pennsylvania 16802, USA.
Riemer Cathy
Hardison Ross C
Burhans Richard
Elnitski Laura
Shah Prachi
Zhang Yi
Blankenberg Daniel
Albert Istvan
Taylor James
Miller Webb
Kent W James
Nekrutenko Anton
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Article Info
Journal
Genome research
Abbr.
Genome Res
ISSN
1088-9051
DOI
10.1101/gr.4086505
Published
2005-10-00
Epub
2005-00-16
Pages
1451-5
Language
English
Region
United States
NLM ID
9518021
PMCID
PMC1240089
Subset
IM
Grants
NHGRI NIH HHS · HG02238 · United States
NIDDK NIH HHS · R56 DK065806 · United States
NIDDK NIH HHS · R01 DK065806 · United States
NIDDK NIH HHS · DK65806 · United States
NHGRI NIH HHS · R01 HG002238 · United States
External Links
PubMed source DOI: 10.1101/gr.4086505 PMC Full Text View journal details
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