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PMID: 15980490 Published · ppublish English Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

PatchDock and SymmDock: servers for rigid and symmetric docking.

Nucleic acids research ·Vol. 33 ·No. Web Server issue ·2005-07-01 ·Pages W363-7

Schneidman-Duhovny D, Inbar Y, Nussinov R, Wolfson HJ

Abstract

Here, we describe two freely available web servers for molecular docking. The PatchDock method performs structure prediction of protein-protein and protein-small molecule complexes. The SymmDock method predicts the structure of a homomultimer with cyclic symmetry given the structure of the monomeric unit. The inputs to the servers are either protein PDB codes or uploaded protein structures. The services are available at http://bioinfo3d.cs.tau.ac.il. The methods behind the servers are very efficient, allowing large-scale docking experiments.

MeSH Terms
Algorithms Internet Ligands Multiprotein Complexes/chemistry Protein Conformation Software User-Computer Interface
Chemicals
Ligands Multiprotein Complexes
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Schneidman-Duhovny Dina
School of Computer Science, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978, Israel.
Inbar Yuval
Nussinov Ruth
Wolfson Haim J
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
1362-4962
DOI
10.1093/nar/gki481
Published
2005-07-01
Pages
W363-7
Language
English
Region
England
NLM ID
0411011
PMCID
PMC1160241
Subset
IM
Grants
NCI NIH HHS · N01CO12400 · United States
NCI NIH HHS · N01-CO-12400 · United States
External Links
PubMed source DOI: 10.1093/nar/gki481 PMC Full Text View journal details
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