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PMID: 15917562 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Detection of qnr in clinical isolates of Escherichia coli from Korea.

Antimicrobial agents and chemotherapy ·Vol. 49 ·No. 6 ·2005-06-00 ·Pages 2522-4

Jeong JY, Yoon HJ, Kim ES, Lee Y, Choi SH, Kim NJ, Woo JH, Kim YS

Abstract

qnr was detected in 2 of 260 Escherichia coli clinical isolates collected from a Korean hospital during the period 2001 to 2003. The two strains were not clonally related. qnr was located in In4 family class 1 integrons of original structure, downstream of orf513 and upstream from another resistance gene (dfrA3b) and a gene of unknown function (orf105). Transfer of the qnr determinant by conjugation could be detected from only one strain.

MeSH Terms

Anti-Infective Agents/pharmacology Drug Resistance, Bacterial/genetics Escherichia coli/drug effects,genetics,isolation & purification Escherichia coli Infections/microbiology Escherichia coli Proteins/genetics Humans Integrons/genetics Korea Microbial Sensitivity Tests Molecular Sequence Data Quinolones/pharmacology Sequence Analysis, DNA

Chemicals

Anti-Infective Agents Escherichia coli Proteins Qnr protein, E coli Quinolones

Authors & Affiliations

8 authors, click to expand affiliations / ORCID

Jeong Jin-Yong

Division of Infectious Diseases, Asan Medical Center and Asan Institute for Life Sciences, University of Ulsan College of Medicine, 388-1 Pungnap-dong, Songpa-gu, Seoul 138-736, Korea.

Yoon Hyun Jung

Kim Eun Sil

Lee Yoola

Choi Sang-Ho

Kim Nam Joong

Woo Jun Hee

Kim Yang Soo

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11 references, click to expand

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Article Info

Journal

Antimicrobial agents and chemotherapy

Abbr.

Antimicrob Agents Chemother

ISSN

0066-4804

DOI

10.1128/AAC.49.6.2522-2524.2005

Published

2005-06-00

Pages

2522-4

Language

English

Region

United States

NLM ID

0315061

PMCID

PMC1140518

Subset

Databases

GENBANK

AY878717, AY878718

External Links

PubMed source DOI: 10.1128/AAC.49.6.2522-2524.2005 PMC Full Text View journal details

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Detection of qnr in clinical isolates of Escherichia coli from Korea.

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