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PMID: 15752453 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Diagnostic system for rapid and sensitive differential detection of pathogens.

Emerging infectious diseases ·Vol. 11 ·No. 2 ·2005-02-00 ·Pages 310-3

Briese T, Palacios G, Kokoris M, Jabado O, Liu Z, Renwick N, Kapoor V, Casas I, Pozo F, Limberger R, Perez-Brena P, Ju J, Lipkin WI

Abstract

Naturally emerging and deliberately released pathogens demand new detection strategies to allow early recognition and containment. We describe a diagnostic system for rapid, sensitive, multiplex discrimination of microbial gene sequences and report its application for detecting 22 respiratory pathogens in clinical samples.

MeSH Terms
Bacterial Infections/diagnosis Bronchoalveolar Lavage Fluid/microbiology,virology Humans Nasal Lavage Fluid/microbiology,virology RNA, Bacterial/chemistry,genetics RNA, Viral/chemistry,genetics Respiratory Tract Infections/diagnosis,microbiology,virology Reverse Transcriptase Polymerase Chain Reaction/methods Sputum/microbiology,virology Virus Diseases/diagnosis
Chemicals
RNA, Bacterial RNA, Viral
Authors & Affiliations
13 authors, click to expand affiliations / ORCID
Briese Thomas
Columbia University, New York, NY 10032, USA.
Palacios Gustavo
Kokoris Mark
Jabado Omar
Liu Zhiqiang
Renwick Neil
Kapoor Vishal
Casas Inmaculada
Pozo Francisco
Limberger Ron
Perez-Brena Pilar
Ju Jingyue
Lipkin W Ian
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12 references, click to expand
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Article Info
Journal
Emerging infectious diseases
Abbr.
Emerg Infect Dis
ISSN
1080-6040
DOI
10.3201/eid1102.040492
Published
2005-02-00
Pages
310-3
Language
English
Region
United States
NLM ID
9508155
PMCID
PMC3320438
Subset
IM
Grants
NIAID NIH HHS · R21 AI056118 · United States
NIAID NIH HHS · AI55466 · United States
NIAID NIH HHS · U54AI057158 · United States
NIAID NIH HHS · R01 AI051292 · United States
NIAID NIH HHS · R21 AI055466 · United States
NIAID NIH HHS · U54 AI057158 · United States
NIAID NIH HHS · AI51292 · United States
NIAID NIH HHS · AI056118 · United States
External Links
PubMed source DOI: 10.3201/eid1102.040492 PMC Full Text View journal details
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