Differentiation of human embryonic stem cells occurs through symmetric cell division.
作者:
Zwaka(Thomas P),Thomson(James A)
状态:
发布时间2005-01-26
, 更新时间 2006-11-15
期刊:
Stem Cells
摘要:
Embryonic (ES) stem cells can be expanded indefinitely, yet retain the ability to form all cell types of the body. Here we report that human ES cells differentiate exclusively by symmetric cell division in each of four distinct differentiation conditions examined. This suggests that, in some respects, ES cells more closely resemble precursor or transit amplifying cells rather than adult stem cells.