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PMID: 15550941 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

Bacterial redox sensors.

Nature reviews. Microbiology ·Vol. 2 ·No. 12 ·2004-12-00 ·Pages 954-66

Green J, Paget MS

Abstract

Redox reactions pervade living cells. They are central to both anabolic and catabolic metabolism. The ability to maintain redox balance is therefore vital to all organisms. Various regulatory sensors continually monitor the redox state of the internal and external environments and control the processes that work to maintain redox homeostasis. In response to redox imbalance, new metabolic pathways are initiated, the repair or bypassing of damaged cellular components is coordinated and systems that protect the cell from further damage are induced. Advances in biochemical analyses are revealing a range of elegant solutions that have evolved to allow bacteria to sense different redox signals.

MeSH Terms
Bacteria/metabolism Bacterial Proteins/metabolism Benzoquinones Cysteine/metabolism Flavin Mononucleotide/metabolism Flavin-Adenine Dinucleotide/metabolism Hemeproteins/metabolism Iron-Sulfur Proteins/metabolism NAD/metabolism NADP/metabolism Oxidation-Reduction Oxidative Stress Signal Transduction
Chemicals
Bacterial Proteins Benzoquinones Hemeproteins Iron-Sulfur Proteins NAD Flavin-Adenine Dinucleotide quinone NADP Flavin Mononucleotide Cysteine
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Green Jeffrey
Krebs Institute for Biomolecular Research, Department of Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield S10 2TN, United Kingdom. Jeff.Green@sheffield.ac.uk
Paget Mark S
Article Info
Journal
Nature reviews. Microbiology
Abbr.
Nat Rev Microbiol
ISSN
1740-1526
Published
2004-12-00
Pages
954-66
Language
English
Region
England
NLM ID
101190261
Subset
IM
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