Connexins: gaps in our knowledge of vascular function.

Physiology (Bethesda, Md.) ·Vol. 19 ·2004-10-00 ·Pages 277-84

Figueroa XF, Isakson BE, Duling BR

Abstract

Gap junctions are common features in the vasculature, long thought to provide a pathway for cell-cell signaling. Emerging understanding of the gap-junctional proteins (connexins) and new tools for their investigation now offer the opportunity to explore the vital role that the gap junctions may play in cardiovascular homeostasis and pathophysiology.

MeSH Terms

Animals Blood Vessels/physiology Connexins/physiology Gap Junctions/physiology Humans

Chemicals

Connexins

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Figueroa Xavier F

Department of Molecular Physiology and Biological Physics, Cardiovascular Research Center, University of Virginia, Charlottesville, Virginia 22908, USA.

Isakson Brant E

Duling Brian R

Article Info

Journal

Physiology (Bethesda, Md.)

Abbr.

Physiology (Bethesda)

ISSN

1548-9213

DOI

10.1152/physiol.00008.2004

Published

2004-10-00

Pages

277-84

Language

English

Region

United States

NLM ID

101208185

Subset

External Links

PubMed source DOI: 10.1152/physiol.00008.2004 View journal details

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Connexins: gaps in our knowledge of vascular function.

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