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PMID: 15324552 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Mice susceptible to SARS coronavirus.

Emerging infectious diseases ·Vol. 10 ·No. 7 ·2004-07-00 ·Pages 1293-6

Wentworth DE, Gillim-Ross L, Espina N, Bernard KA

Abstract

Murine models of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) will greatly advance research on this emerging virus. When BALB/c mice were simultaneously inoculated intranasally and orally, replication of SARS-CoV was found in both lung and intestinal tissue.

MeSH Terms
Animals Disease Models, Animal Humans Intestines/virology Lung/virology Mice Mice, Inbred BALB C SARS Virus/pathogenicity Severe Acute Respiratory Syndrome/physiopathology Virus Replication
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Wentworth David E
New York Department of Health, Albany 12201-2002, USA. dwentwor@wadsworth.org
Gillim-Ross Laura
Espina Noel
Bernard Kristen A
References (10)
10 references, click to expand
  1. Identification of a novel coronavirus in patients with severe acute respiratory syndrome.
    N Engl J Med. 2003 May 15;348(20):1967-76 PMID: 12690091
  2. A novel coronavirus associated with severe acute respiratory syndrome.
    N Engl J Med. 2003 May 15;348(20):1953-66 PMID: 12690092
  3. Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study.
    Lancet. 2003 May 24;361(9371):1767-72 PMID: 12781535
  4. Lung pathology of fatal severe acute respiratory syndrome.
    Lancet. 2003 May 24;361(9371):1773-8 PMID: 12781536
  5. Discovery of novel human and animal cells infected by the severe acute respiratory syndrome coronavirus by replication-specific multiplex reverse transcription-PCR.
    J Clin Microbiol. 2004 Jul;42(7):3196-206 PMID: 15243082
  6. Mechanisms and enzymes involved in SARS coronavirus genome expression.
    J Gen Virol. 2003 Sep;84(Pt 9):2305-15 PMID: 12917450
  7. Unique and conserved features of genome and proteome of SARS-coronavirus, an early split-off from the coronavirus group 2 lineage.
    J Mol Biol. 2003 Aug 29;331(5):991-1004 PMID: 12927536
  8. Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China.
    Science. 2003 Oct 10;302(5643):276-8 PMID: 12958366
  9. Virology: SARS virus infection of cats and ferrets.
    Nature. 2003 Oct 30;425(6961):915 PMID: 14586458
  10. Newly discovered coronavirus as the primary cause of severe acute respiratory syndrome.
    Lancet. 2003 Jul 26;362(9380):263-70 PMID: 12892955
Article Info
Journal
Emerging infectious diseases
Abbr.
Emerg Infect Dis
ISSN
1080-6040
DOI
10.3201/eid1007.031119
Email
dwentwor@wadsworth.org
Published
2004-07-00
Pages
1293-6
Language
English
Region
United States
NLM ID
9508155
PMCID
PMC3323317
Subset
IM
Grants
NIAID NIH HHS · N01AI25490 · United States
PHS HHS · U54A17158 · United States
NIAID NIH HHS · U54 AI057158-019001 · United States
NIAID NIH HHS · U54 AI057158 · United States
ODCDC CDC HHS · U901CCU216988-03 · United States
External Links
PubMed source DOI: 10.3201/eid1007.031119 PMC Full Text View journal details
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