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PMID: 15316557 Published · ppublish English Journal Article

Molecular marker genotypes, heterozygosity and genetic interactions explain heterosis in Arabidopsis thaliana.

Heredity ·Vol. 94 ·No. 3 ·2005-03-00 ·Pages 295-304

Syed NH, Chen ZJ

Abstract

The underlying mechanisms for hybrid vigor or heterosis are elusive. Here we report a population of recombinant inbred lines (RILs), derived from the two ecotypes, Col and Ler, which can serve as a permanent resource for studying the molecular basis of hybrid vigor in Arabidopsis. Using a North Carolina mating design III (NCIII), we determined the additive and dominant nature of gene action in this population. We detected heterosis among crosses of RILs with one of the two parents (Col and Ler) and analyzed genotypes and heterozygosities for RILs and test cross families (RILs crossed to Col and Ler) using a total of 446 published molecular markers. The performance of RILs and additive and dominant components in the test cross families were used to analyze QTLs for 16 traits, using QTL cartographer and composite interval mapping with 1,000 permutations for each trait. Our data suggest that locus-specific and/or genome-wide differential heterozygosity, including epistasis, plays an important role in the generation of the observed heterosis. Furthermore, the hybrid vigor occurred between two closely related ecotypes, and provides a general mechanism for novel variation generated between genetically similar materials.

MeSH Terms
Arabidopsis/genetics Environment Epistasis, Genetic Genetic Markers Genetic Variation Genotype Heterozygote Hybrid Vigor/genetics
Chemicals
Genetic Markers
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Syed N H
Plant Sciences, University of Dundee at Scottish Crop Research Institute, Dundee DD2 5DA, UK. nsyed@scri.sari.ac.uk
Chen Z J
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Article Info
Journal
Heredity
Abbr.
Heredity (Edinb)
ISSN
0018-067X
DOI
10.1038/sj.hdy.6800558
Email
nsyed@scri.sari.ac.uk
Published
2005-03-00
Pages
295-304
Language
English
Region
England
NLM ID
0373007
PMCID
PMC2041864
Subset
IM
Grants
NIGMS NIH HHS · R01 GM067015 · United States
NIGMS NIH HHS · R01 GM067015-01A1 · United States
External Links
PubMed source DOI: 10.1038/sj.hdy.6800558 PMC Full Text View journal details
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