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PMID: 15242630
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English
Journal Article
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Epithelium-mesenchyme: a balancing act of RhoGAP and RhoGEF.
Abstract
Transitions between epithelium and mesenchyme, in either direction, contribute repeatedly to animal development. Three striking papers suggest that distinct components with opposite activities, which together form a complex known for its role in cytokinesis, control these opposite transitions.
MeSH Terms
Adherens Junctions/metabolism
Animals
Caenorhabditis elegans/embryology,metabolism
Caenorhabditis elegans Proteins/metabolism
Cell Division/physiology
Cell Movement/physiology
Cell Polarity/physiology
Drosophila/embryology,metabolism
Drosophila Proteins/metabolism
Epithelium/embryology
GTPase-Activating Proteins/metabolism
Guanine Nucleotide Exchange Factors/metabolism
Kinesins/metabolism
Mesoderm/cytology
Microtubules/metabolism
Models, Biological
Rho Guanine Nucleotide Exchange Factors
rho GTP-Binding Proteins/metabolism
Chemicals
Caenorhabditis elegans Proteins
Drosophila Proteins
GTPase-Activating Proteins
Guanine Nucleotide Exchange Factors
Pbl protein, Drosophila
Rho Guanine Nucleotide Exchange Factors
ZEN-4 protein, C elegans
rho GTPase-activating protein
Kinesins
rho GTP-Binding Proteins
Article Info
Journal
Current biology : CB
Abbr.
Curr Biol
ISSN
0960-9822
Published
2004-07-13
Pages
R508-10
Language
English
Region
England
NLM ID
9107782
Subset
IM
Corrections
CommentOn
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