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PMID: 15239820 Published · ppublish English Journal Article Review

The uses of genome-wide yeast mutant collections.

Genome biology ·Vol. 5 ·No. 7 ·2004-00-00 ·Pages 229

Scherens B, Goffeau A

Abstract

We assess five years of usage of the major genome-wide collections of mutants from Saccharomyces cerevisiae: single deletion mutants, double mutants conferring 'synthetic' lethality and the 'TRIPLES' collection of mutants obtained by random transposon insertion. Over 100 experimental conditions have been tested and more than 5,000 novel phenotypic traits have been assigned to yeast genes using these collections.

MeSH Terms
Genetics/trends Genome, Fungal Humans Mutation/genetics Saccharomyces cerevisiae/genetics
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Scherens Bart
Institut des Sciences de la Vie, Université Catholique de Louvain, Croix du Sud 2-20, 1348 Louvain-la-Neuve, Belgium.
Goffeau Andre
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Article Info
Journal
Genome biology
Abbr.
Genome Biol
ISSN
1474-760X
DOI
10.1186/gb-2004-5-7-229
Published
2004-00-00
Epub
2004-00-25
Pages
229
Language
English
Region
England
NLM ID
100960660
PMCID
PMC463272
Subset
IM
External Links
PubMed source DOI: 10.1186/gb-2004-5-7-229 PMC Full Text View journal details
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