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PMID: 15229473 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Review

Class-switch recombination: interplay of transcription, DNA deamination and DNA repair.

Nature reviews. Immunology ·Vol. 4 ·No. 7 ·2004-07-00 ·Pages 541-52

Chaudhuri J, Alt FW

Abstract

暂无摘要

MeSH Terms

Animals Cytidine Deaminase Cytosine Deaminase/physiology DNA Repair Deamination Genes, Immunoglobulin Humans Immunoglobulin Class Switching/genetics Immunoglobulin Heavy Chains/genetics Macromolecular Substances Mice Models, Genetic Plasmids/genetics Somatic Hypermutation, Immunoglobulin/genetics Transcription, Genetic VDJ Recombinases/physiology

Chemicals

Immunoglobulin Heavy Chains Macromolecular Substances VDJ Recombinases AICDA (activation-induced cytidine deaminase) Cytosine Deaminase Cytidine Deaminase

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Chaudhuri Jayanta

Howard Hughes Medical Institute, Center for Blood Research and Department of Genetics, Harvard University Medical School, Boston, Massachusetts 02115, USA.

Alt Frederick W

Article Info

Journal

Nature reviews. Immunology

Abbr.

Nat Rev Immunol

ISSN

1474-1733

DOI

10.1038/nri1395

Published

2004-07-00

Pages

541-52

Language

English

Region

England

NLM ID

101124169

Subset

Corrections

ErratumIn

External Links

PubMed source DOI: 10.1038/nri1395 View journal details

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Class-switch recombination: interplay of transcription, DNA deamination and DNA repair.

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