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题目:: Multiple roles of canonical Wnt signaling in cell cycle progression and cell lineage specification in neural development.
作者:: Sommer(Lukas)
状态:: 发布时间2004-07-28 , 更新时间 2005-11-17
期刊:: Cell Cycle
摘要:: Signaling by the canonical Wnt pathway has multiple functions in stem cells. It can either control stem cell expansion or--as we have recently demonstrated with neural crest stem cells-influence cell lineage decisions by promoting specific fates at the expense of others. Thus, the role of canonical Wnt in stem cells is dependent on cell--intrinsic properties that determine how a cell responds to Wnt. The molecular basis for the functional diversity of Wnt in different stem cell types remains to be elucidated.
语言:: eng
DOI:

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