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PMID: 1509519 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

The TATA-binding protein: a central role in transcription by RNA polymerases I, II and III.

Trends in genetics : TIG ·Vol. 8 ·No. 8 ·1992-08-00 ·Pages 284-8

White RJ, Jackson SP

Abstract

The TATA-box-binding protein, first noted for its association with the general transcription factor TFIID, has recently been shown to be required for transcription by all three classes of nuclear RNA polymerase found in eukaryotes. As such, it plays a unique and pivotal role in gene expression in higher organisms.

MeSH Terms

Animals DNA-Binding Proteins/metabolism Humans RNA Polymerase I/metabolism RNA Polymerase II/metabolism RNA Polymerase III/metabolism TATA Box TATA-Box Binding Protein Transcription Factors/metabolism Transcription, Genetic

Chemicals

DNA-Binding Proteins TATA-Box Binding Protein Transcription Factors RNA Polymerase II RNA Polymerase I RNA Polymerase III

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

White R J

Wellcome/CRC Institute, Cambridge, UK.

Jackson S P

Article Info

Journal

Trends in genetics : TIG

Abbr.

Trends Genet

ISSN

0168-9525

DOI

10.1016/0168-9525(92)90255-3

Published

1992-08-00

Pages

284-8

Language

English

Region

England

NLM ID

8507085

Subset

Grants

Wellcome Trust · United Kingdom

External Links

PubMed source DOI: 10.1016/0168-9525(92)90255-3 View journal details

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The TATA-binding protein: a central role in transcription by RNA polymerases I, II and III.

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