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题目:: Murine B-cell leukemia lymphoma (BCL1) cells as a target for NK cell-mediated immunotherapy.
作者:: Weiss(L),Reich(S),Mandelboim(O),Slavin(S)
状态:: 发布时间2004-05-21 , 更新时间 2008-11-21
期刊:: Bone Marrow Transplant
摘要:: Natural killer (NK) cells are important for their ability to recognize and lyse tumor cells and virus infected cells. NK cells express triggering receptors that are specific for non-MHC ligands. This article describes the 35S release cytotoxic assay, which measures the ability of NK cells derived from spleen cells taken from polyIC-treated mice to lyse B-cell leukemia (BCL1) cells. BCL1 cells express ligands for NKp46 on the cell surface membrane and they are sensitive to allogeneic but not syngeneic IL-2 activated natural killer cells.
语言:: eng
DOI:

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