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PMID: 15018654 Published · epublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't

Array-A-Lizer: a serial DNA microarray quality analyzer.

BMC bioinformatics ·Vol. 5 ·2004-02-09 ·Pages 12

Petri A, Fleckner J, Matthiessen MW

Abstract

The proliferate nature of DNA microarray results have made it necessary to implement a uniform and quick quality control of experimental results to ensure the consistency of data across multiple experiments prior to actual data analysis. Array-A-Lizer is a small and convenient stand-alone tool providing the necessary initial analysis of hybridization quality of an unlimited number of microarray experiments. The experiments are analyzed for even hybridization across the slide and between fluorescent dyes in two-color experiments in spotted DNA microarrays. Array-A-Lizer allows the expedient determination of the quality of multiple DNA microarray experiments allowing for a rapid initial screening of results before progressing to further data analysis. Array-A-Lizer is directed towards speed and ease-of-use allowing both the expert and non-expert microarray researcher to rapidly assess the quality of multiple microarray hybridizations. Array-A-Lizer is available from the Internet as both source code and as a binary installation package.

MeSH Terms
Computer Graphics/statistics & numerical data Gene Expression Profiling/standards Oligonucleotide Array Sequence Analysis/standards Quality Control Software/standards User-Computer Interface
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Petri Andreas
Department of Molecular Genetics, Novo Nordisk A/S, Bagsvaerd, 2880, Denmark. andp@novonordisk.com
Fleckner Jan
Matthiessen Mads Wichmann
References (1)
1 references, click to expand
  1. Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation.
    Nucleic Acids Res. 2002 Feb 15;30(4):e15 PMID: 11842121
Article Info
Journal
BMC bioinformatics
Abbr.
BMC Bioinformatics
ISSN
1471-2105
Published
2004-02-09
Epub
2004-00-09
Pages
12
Language
English
Region
England
NLM ID
100965194
PMCID
PMC356907
Subset
IM
Analysis Services
Analysis Services

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