Stimulating capacity of human lymphoid cell subpopulations in mixed lymphocyte cultures.
作者:
Albrechtsen(D),Lied(M)
状态:
发布时间1978-08-14
, 更新时间 2004-11-17
期刊:
Scand J Immunol
摘要:
The content and yield or B cells, T cells and monocytes were investigated in cell fractions separated from human peripheral blood by various techniques. These cell fractions, which were highly enriched for either B cells, T cells or monocytes, were tested for their capacity to stimulate allogenic peripheral blood mononuclear cells in mixed lymphocyte cultures (MLC). B cells were found to be strongly stimulatory. Monocytes stimulated strongly at low stimulator/responder cell ratios, while less stimulation was observed using larger amounts of cells. T cells were demonstrated to stimulate weakly, if at all.