Congenital SPCA deficiency: a hitherto unrecognized coagulation defect with hemorrhage rectified by serum and serum fractions.

The Journal of clinical investigation ·Vol. 30 ·No. 6 ·1951-06-00 ·Pages 596-608

ALEXANDER B, GOLDSTEIN R, LANDWEHR G, COOK CD

Abstract

暂无摘要

Keywords

BLOOD COAGULATION HEMORRHAGIC DIATHESIS

MeSH Terms

Blood Coagulation Blood Coagulation Disorders Hemorrhage Hemorrhagic Disorders Humans

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

ALEXANDER B

GOLDSTEIN R

LANDWEHR G

COOK C D

References (8)

8 references, click to expand

Hypoprothrombinemia; studies of a case of the idiopathic type and the effect of serum administration.
Blood. 1949 Dec;4(12):1298-1309 PMID: 15395436
The prothrombin conversion accelerator of serum (SPCA): its partial purification and its properties compared with serum AC-globulin.
J Clin Invest. 1950 Jul;29(7):881-95 PMID: 15436856
Coagulation defect in hepatic disorders: deficiency of prothrombin-conversion accessory substances.
J Clin Invest. 1950 Jun;29(6):795-6 PMID: 15436674
Congenital hypoprothrombinemia; a case study with particular reference to the role of non-prothrombin factors in the conversion of prothrombin.
Am J Med. 1950 Feb;8(2):255-9 PMID: 15405889
Prothrombin consumption, serum prothrombic activity and prothrombin conversion accelerator in hemophilia and thrombocytopenia.
J Clin Invest. 1949 Nov;28(6 Pt 2):1511-6 PMID: 15395954
A Prothrombin Conversion Accelerator in Serum.
Science. 1949 May 27;109(2839):545 PMID: 17752841
HUMAN PROTHROMBIN: QUANTITATIVE STUDIES ON THE PLASMA LABILE FACTOR AND THE RESTORATIVE EFFECTS OF NORMAL, HYPOFI-BRINOGENEMIC, AND HEMOPHILIC PLASMA ON THE PROTHROMBIN OF STORED PLASMA.
J Clin Invest. 1949 Jan;28(1):24-31 PMID: 16695655
Evolution of a prothrombin conversion accelerator in stored human plasma and prothrombin fractions.
Am J Physiol. 1949 Nov;159(2):322-31 PMID: 15393474

Article Info

Journal

The Journal of clinical investigation

Abbr.

J Clin Invest

ISSN

0021-9738

DOI

Published

1951-06-00

Pages

596-608

Language

English

Region

United States

NLM ID

7802877

PMCID

PMC436294

Subset

External Links

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