Sustained hyperlipemia induced in rabbits by means of intravenously injected surface-active agents.

The Journal of experimental medicine ·Vol. 93 ·No. 4 ·1951-04-01 ·Pages 373-84

KELLNER A, CORRELL JW, LADD AT

Abstract

The intravenous injection of the surface-active agents Tween 80 and Triton A20 into rabbits fed a normal diet resulted in marked and sustained elevations of the cholesterol, phospholipid, and total lipid content of their blood. The increase in phospholipid in general paralleled that of the blood cholesterol. The implications of the findings are briefly discussed.

Keywords

BLOOD

MeSH Terms

Animals Blood Cholesterol Hyperlipidemias Injections, Intravenous Rabbits Surface-Active Agents

Chemicals

Surface-Active Agents Cholesterol

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

KELLNER A

CORRELL J W

LADD A T

References (7)

7 references, click to expand

The stabilization of serum lipid emulsions by serum phospholipids.
J Exp Med. 1949 Nov;90(5):409-24 PMID: 18143586
The effect of wetting agents on the growth of tubercle bacilli.
J Exp Med. 1948 Jul;88(1):81-8 PMID: 18871880
THE LS-ANTIGEN OF VACCINIA : II. ISOLATION OF A SINGLE SUBSTANCE CONTAINING BOTH L- AND S-ACTIVITY.
J Exp Med. 1942 Jan 31;75(2):165-78 PMID: 19871174
The influence of intravenously administered surface-active agents on the development of experimental atherosclerosis in rabbits.
J Exp Med. 1951 Apr 1;93(4):385-98 PMID: 14824410
EXPERIMENTAL LIPEMIA IN RABBITS.
J Exp Med. 1909 Jul 17;11(4):553-60 PMID: 19867266
A LONG TERM STUDY OF THE VARIATION OF SERUM CHOLESTEROL IN MAN.
J Clin Invest. 1939 Jan;18(1):45-9 PMID: 16694643
Production of atheromatosis in the aorta of the bird by the administration of diethylstilbestrol.
J Exp Med. 1948 Sep 1;88(3):373-88 PMID: 18881496

Article Info

Journal

The Journal of experimental medicine

Abbr.

J Exp Med

ISSN

0022-1007

DOI

10.1084/jem.93.4.373

Published

1951-04-01

Pages

373-84

Language

English

Region

United States

NLM ID

2985109R

PMCID

PMC2136077

Subset

External Links

PubMed source DOI: 10.1084/jem.93.4.373 PMC Full Text View journal details

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Sustained hyperlipemia induced in rabbits by means of intravenously injected surface-active agents.

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