Abstract
When applied within a low-strength electric field (+/- 12 V/cm) with a low current density (+/- 2.1 mA/cm2), several industrial biocides exhibited enhanced killing action against Pseudomonas aeruginosa biofilms grown on stainless steel studs. Biocide concentrations lower than those necessary to kill planktonic cells of P. aeruginosa (1, 5, and 10 ppm of the active ingredients of kathon, glutaraldehyde, and quaternary ammonium compound, respectively) were bactericidal within 24 h when applied within our electrified device.
MeSH Terms
Dimethylamines/pharmacology
Disinfectants/pharmacology
Electricity
Glutaral/pharmacology
Pseudomonas aeruginosa/drug effects
Thiazoles/pharmacology
Chemicals
Dimethylamines
Disinfectants
Thiazoles
3-isothiazolone
dimethylamine
Glutaral
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Blenkinsopp S A
Natural Sciences and Engineering Research Council Biofilm Group, University of Calgary, Alberta, Canada.
Khoury A E
Costerton J W
References (6)
6 references, click to expand
-
Legionella pneumophila grows adherent to surfaces in vitro and in situ.
Infect Control Hosp Epidemiol. 1989 Sep;10(9):408-15
PMID: 2794466
-
Biofilm Dynamics and Kinetics during High-Rate Sulfate Reduction under Anaerobic Conditions.
Appl Environ Microbiol. 1987 Jan;53(1):27-32
PMID: 16347263
-
Laboratory-based model of microbiologically induced corrosion of copper.
Appl Environ Microbiol. 1991 Jul;57(7):1956-62
PMID: 16348520
-
Inactivation of biofilm bacteria.
Appl Environ Microbiol. 1988 Oct;54(10):2492-9
PMID: 2849380
-
Tobramycin resistance of Pseudomonas aeruginosa cells growing as a biofilm on urinary catheter material.
Antimicrob Agents Chemother. 1985 Apr;27(4):619-24
PMID: 3923925
-
Effect of hydrogenase and mixed sulfate-reducing bacterial populations on the corrosion of steel.
Appl Environ Microbiol. 1991 Oct;57(10):2804-9
PMID: 16348560