Tumour invasion: effects of cell adhesion and motility.
作者:
Van Roy(F),Mareel(M)
状态:
发布时间2004-01-20
, 更新时间 2004-01-20
期刊:
Trends Cell Biol
摘要:
Metastasis is the major cause of failure in cancer therapy. Recent studies of the molecular cell biology of the metastatic process have provided new insights into the mechanisms of cell-cell adhesion, cell-substrate adhesion and cell motility that underly invasion by tumour cells. In this review, Van Roy and Mareel discuss the role of proteins with invasion-promoting and invasion-suppressing functions in metastasis.