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题目:: Syndecan-2 expression enhances adhesion and proliferation of stably transfected Swiss 3T3 cells.
作者:: Villena(Joan),Berndt(Christine),Granés(Francesc),Reina(Manuel),Vilaró(Senén)
状态:: 发布时间2003-12-03 , 更新时间 2006-11-15
期刊:: Cell Biol Int
摘要:: Syndecans (heparan sulfate proteoglycans) participate in cell-cell and cell-matrix adhesion and are co- and low-affinity receptors for growth factors and enzymes, respectively. We examined the influence of stable syndecan-2 expression in Swiss 3T3 cells on cell-adhesion and proliferation. Higher syndecan-2 expression changed cell morphology and increased spreading and adhesion in these cells and proliferation induced by FCS and FGF-2. This emphasizes the role of syndecan-2 in the integration of signals from soluble and insoluble factors.
语言:: eng
DOI:

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