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PMID: 1458448 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

A t(2;3)(q12-13;p24-25) in follicular thyroid adenomas.

Cancer genetics and cytogenetics ·Vol. 64 ·No. 1 ·1992-11-00 ·Pages 38-41

Sozzi G, Miozzo M, Cariani TC, Bongarzone I, Pilotti S, Pierotti MA, Della Porta G

Abstract

We report the cytogenetic analysis of five cases of follicular thyroid adenoma. In two of them, we observed an identical t(2;3)(q12-13;p24-25) as a unique chromosome change. A third case showed a hyperdiploid karyotype with trisomies of chromosomes 7 and 12. Two cases had a normal diploid karyotype. These changes could define subgroups of follicular adenomas endowed with different malignant potential.

MeSH Terms

Adenocarcinoma/genetics Adult Aneuploidy Chromosomes, Human, Pair 12 Chromosomes, Human, Pair 2 Chromosomes, Human, Pair 3 Chromosomes, Human, Pair 7 Female Humans Karyotyping Middle Aged Thyroid Neoplasms/genetics Translocation, Genetic Trisomy

Authors & Affiliations

7 authors, click to expand affiliations / ORCID

Sozzi G

Division of Experimental Oncology A, Istituto Nazionale Tumori, Milan, Italy.

Miozzo M

Cariani T C

Bongarzone I

Pilotti S

Pierotti M A

Della Porta G

Article Info

Journal

Cancer genetics and cytogenetics

Abbr.

Cancer Genet Cytogenet

ISSN

0165-4608

DOI

10.1016/0165-4608(92)90320-8

Published

1992-11-00

Pages

38-41

Language

English

Region

United States

NLM ID

7909240

Subset

External Links

PubMed source DOI: 10.1016/0165-4608(92)90320-8 View journal details

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A t(2;3)(q12-13;p24-25) in follicular thyroid adenomas.

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