Interaction between bacteriophage lambda and its Escherichia coli host.

Current opinion in genetics & development ·Vol. 2 ·No. 5 ·1992-10-00 ·Pages 727-38

Friedman DI

Abstract

Bacteriophage lambda relies to a large extent on processes requiring interactions between viral- and host-encoded proteins for its lytic growth, establishment of lysogeny, and release from the prophage state. Both biochemical and genetic studies of these interactions have yielded new information about important host and lambda functions. In particular, mutations in Escherichia coli that compromise lambda DNA replication, genome packaging, transcription elongation, and site-specific recombination have led to the identification of bacterial genes whose products are chaperones, transcription factors, or DNA-binding proteins.

Related Genes

MeSH Terms

Bacterial Proteins/genetics,metabolism Bacteriophage lambda/genetics,physiology DNA-Binding Proteins/genetics,metabolism Escherichia coli/genetics,physiology Gene Expression Regulation, Bacterial Gene Expression Regulation, Viral Lysogeny RNA-Binding Proteins/genetics,metabolism Viral Proteins/genetics,metabolism Virus Activation Virus Integration Virus Replication

Chemicals

Bacterial Proteins DNA-Binding Proteins RNA-Binding Proteins Viral Proteins rexB protein, Bacteriophage lambda

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Friedman D I

University of Michigan, Ann Arbor.

Article Info

Journal

Current opinion in genetics & development

Abbr.

Curr Opin Genet Dev

ISSN

0959-437X

DOI

10.1016/s0959-437x(05)80133-9

Published

1992-10-00

Pages

727-38

Language

English

Region

England

NLM ID

9111375

Subset

External Links

PubMed source DOI: 10.1016/s0959-437x(05)80133-9 View journal details

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