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PMID: 1452366 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Encystation of Giardia lamblia leads to expression of antigens recognized by antibodies against conserved heat shock proteins.

Infection and immunity ·Vol. 60 ·No. 12 ·1992-12-00 ·Pages 5312-5

Reiner DS, Shinnick TM, Ardeshir F, Gillin FD

Abstract

During in vitro encystation, Giardia lamblia expresses several stage-specific proteins which are recognized in immunoblots by antisera raised against antigens from three different pathogens. The antigens belong to two different families of conserved stress proteins: (i) HSP60 purified from Legionella pneumophila and recombinant HSP60 from Mycobacterium bovis BCG and (ii) recombinant HSP70 from Plasmodium falciparum.

MeSH Terms
Animals Antigens, Protozoan/analysis Giardia lamblia/immunology,physiology Heat-Shock Proteins/immunology Immune Sera/immunology Rabbits
Chemicals
Antigens, Protozoan Heat-Shock Proteins Immune Sera
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Reiner D S
Department of Pathology, University of California, San Diego 92103.
Shinnick T M
Ardeshir F
Gillin F D
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29 references, click to expand
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Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
DOI
10.1128/iai.60.12.5312-5315.1992
Published
1992-12-00
Pages
5312-5
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC258313
Subset
IM
External Links
PubMed source DOI: 10.1128/iai.60.12.5312-5315.1992 PMC Full Text View journal details
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