Amplification of AML1 in acute lymphoblastic leukemia is associated with a poor outcome.

Child Child, Preschool Core Binding Factor Alpha 2 Subunit DNA-Binding Proteins/genetics Disease-Free Survival Gene Amplification Humans Immunophenotyping Neoplasm Proteins/genetics Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics,mortality Prognosis Proto-Oncogene Proteins Time Factors Transcription Factors/genetics Treatment Outcome

Core Binding Factor Alpha 2 Subunit DNA-Binding Proteins Neoplasm Proteins Proto-Oncogene Proteins RUNX1 protein, human Transcription Factors