A theory of endothelial control of corneal hydration.

American journal of optometry and physiological optics ·Vol. 54 ·No. 7 ·1977-07-00 ·Pages 439-44

Rehm WS, Spangler SG

Abstract

The details of our previously described theory of how the endothelium controls corneal hydration in the absence of the epithelium are provided. A central postulate is that the endothelium can produce across its limiting plasma membranes an osmotic gradient that reduces stromal swelling pressure so that it does not exceed intraocular pressure during thinning of a swollen cornea.

MeSH Terms

Adenosine Triphosphatases/metabolism Aqueous Humor/metabolism Bicarbonates/metabolism Biological Transport, Active Cell Membrane/metabolism Cornea/enzymology,metabolism Descemet Membrane/metabolism Extracellular Space/metabolism Humans Hydrostatic Pressure Models, Biological Potassium/metabolism Sodium/metabolism Water-Electrolyte Balance

Chemicals

Bicarbonates Sodium Adenosine Triphosphatases Potassium

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Rehm W S

Spangler S G

Article Info

Journal

American journal of optometry and physiological optics

Abbr.

Am J Optom Physiol Opt

ISSN

0093-7002

DOI

10.1097/00006324-197707000-00002

Published

1977-07-00

Pages

439-44

Language

English

Region

United States

NLM ID

0417614

Subset

External Links

PubMed source DOI: 10.1097/00006324-197707000-00002

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A theory of endothelial control of corneal hydration.

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