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PMID: 14403926 Published · ppublish English Journal Article

Isolated rabbit atria with sympathetic nerve supply.

British journal of pharmacology and chemotherapy ·Vol. 14 ·1959-09-00 ·Pages 372-6

HUKOVIC S

Abstract

The atria of the rabbit heart have been isolated together with their sympathetic nerves, so that the latter could be stimulated and the effect on the rate and amplitude of beating could be measured. Cocaine and phenoxybenzamine increased the response to stimulation. When the preparation was from rabbits previously given reserpine, stimulation of the sympathetic nerves caused inhibition. This inhibition was increased by eserine and abolished by atropine.

Keywords
HEART/pharmacology
MeSH Terms
Animals Autonomic Pathways Heart/pharmacology Heart Atria Phenoxybenzamine Physostigmine Rabbits Reserpine Sympathetic Nervous System
Chemicals
Phenoxybenzamine Reserpine Physostigmine
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
HUKOVIC S
References (5)
5 references, click to expand
  1. The responses of the musculature of the colon of the rabbit to stimulation, in vitro, of the parasympathetic and of the sympathetic outflows.
    J Physiol. 1955 Jun 28;128(3):557-76 PMID: 13243349
  2. The sympathetic dilator fibres in the muscles of the cat and dog.
    J Physiol. 1935 Mar 15;83(4):483-501 PMID: 16994648
  3. The output of sympathetic transmitter from the spleen of the cat.
    J Physiol. 1957 Aug 29;138(1):81-102 PMID: 13463800
  4. The chemical transmission of secretory impulses to the sweat glands of the cat.
    J Physiol. 1934 Aug 24;82(1):121-8 PMID: 16994562
  5. The effect on the isolated rabbit heart of vagal stimulation and its modification by cocaine, hexamethonium and ouabain.
    J Physiol. 1956 Mar 28;131(3):678-89 PMID: 13320365
Article Info
Journal
British journal of pharmacology and chemotherapy
Abbr.
Br J Pharmacol Chemother
ISSN
0366-0826
Published
1959-09-00
Pages
372-6
Language
English
Region
England
NLM ID
0154627
PMCID
PMC1481743
Subset
OM
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