A study, by simultaneous clearance techniques, of salicylate excretion in man: effect of alkalinization of the urine by bicarbonate administration; effect of probenecid.

The Journal of clinical investigation ·Vol. 34 ·No. 5 ·1955-05-00 ·Pages 711-21

GUTMAN A, YU TF, SIROTA JH

Abstract

暂无摘要

Keywords

BICARBONATES/effects PROBENECID/effects SALICYLATES/in urine URINE

MeSH Terms

Bicarbonates/pharmacology Biological Transport Body Fluids Cell Physiological Phenomena Humans Kinetics Male Probenecid/pharmacology Salicylates/urine Urine

Chemicals

Bicarbonates Salicylates Probenecid

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

GUTMAN A

YU T F

SIROTA J H

References (10)

10 references, click to expand

Benzoyl coenzyme A and hippurate synthesis.
J Biol Chem. 1953 Aug;203(2):925-34 PMID: 13084662
The kidney.
Annu Rev Physiol. 1954;16:269-304 PMID: 13171827
Glycine N-acylase: purification and properties.
J Biol Chem. 1954 May;208(1):263-75 PMID: 13174534
'Benemid', p-(di-n-propylsulfamyl)-benzoic acid: inhibition of glycine conjugative reactions.
Proc Soc Exp Biol Med. 1950 Aug;74(4):772-5 PMID: 14781177
Relation of rate of excretion of salicylate to urinary acidity.
Arch Int Pharmacodyn Ther. 1951 May;86(3):303-10 PMID: 14838640
On the renal excretion of salicylate.
Acta Pharmacol Toxicol (Copenh). 1951;7(3):243-58 PMID: 14856757
Effect of benemid (p-[di-n-propylsulfamyl]-benzoic acid) on urate clearance and other discrete renal functions in gouty subjects.
J Clin Invest. 1952 Jul;31(7):692-701 PMID: 14938444
The influence of urinary pH on the renal excretion of salicyl derivatives during aspirin therapy.
J Lab Clin Med. 1950 Feb;35(2):237-48 PMID: 15404238
Determination of inulin by means of resorcinol.
Proc Soc Exp Biol Med. 1950 May;74(1):117-20 PMID: 15430407
THE RENAL CLEARANCES OF SUBSTITUTED HIPPURIC ACID DERIVATIVES AND OTHER AROMATIC ACIDS IN DOG AND MAN.
J Clin Invest. 1945 May;24(3):388-404 PMID: 16695228

Article Info

Journal

The Journal of clinical investigation

Abbr.

J Clin Invest

ISSN

0021-9738

DOI

10.1172/JCI103124

Published

1955-05-00

Pages

711-21

Language

English

Region

United States

NLM ID

7802877

PMCID

PMC438682

Subset

External Links

PubMed source DOI: 10.1172/JCI103124 PMC Full Text View journal details

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A study, by simultaneous clearance techniques, of salicylate excretion in man: effect of alkalinization of the urine by bicarbonate administration; effect of probenecid.

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