PATHOGENESIS OF INFLAMMATION. II. IN VIVO OBSERVATIONS OF THE INFLAMMATORY EFFECTS OF ACTIVATED HAGEMAN FACTOR AND BRADYKININ.
Activated Hageman factor, when injected into the rabbit ear chamber, produces a delayed and prolonged inflammatory response characterized by prominent sticking and emigration of leucocytes. In contrast, preformed bradykinin evokes an immediate and more transient response in which leucocytic emigration occurs less frequently. It is concluded that either Hageman factor produces its inflammatory effects by mechanisms other than kinin release, or bradykinin released endogenously has effects quite different from those resulting from a single injection of the exogenous material.
11 references, click to expand
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The purification of activated Hageman factor (activated factor XII).Biochemistry. 1962 Nov;1:967-75 PMID: 13973274
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KININ-FORMING ACTIVITY AND HISTAMINE IN LYMPH AFTER TISSUE INJURY.J Physiol. 1963 Dec;169:568-83 PMID: 14082119
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ACTIVATION OF HAGEMAN FACTOR BY SOLUTIONS OF ELLAGIC ACID.J Lab Clin Med. 1964 Mar;63:359-77 PMID: 14165678
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Modifications of the rabbit ear chamber technique.Science. 1949 Dec 16;110(2868):665 PMID: 15396024
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Studies on the action of Hageman factor: evidence that activated Hageman factor in turn activates plasma thromboplastin antecedent.J Clin Invest. 1961 May;40:803-19 PMID: 13739760
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PATHOGENESIS OF INFLAMMATION. I. THE PRODUCTION OF AN INFLAMMATORY SUBSTANCE FROM RABBIT GRANULOCYTES IN VITRO AND ITS RELATIONSHIP TO LEUCOCYTE PYROGEN.J Exp Med. 1964 Jul 1;120:57-82 PMID: 14194393
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THE INDUCTION OF PERMEABILITY-INCREASING ACTIVITY IN HUMAN PLASMA BY ACTIVATED HAGEMAN FACTOR.Br J Exp Pathol. 1964 Jun;45:328-45 PMID: 14173175
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Delayed leucocytic emigration after intra-dermal injections and thermal injury.J Pathol Bacteriol. 1961 Oct;82:421-9 PMID: 14450146
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Role of Hageman factor in the activation of vasodilator activity in human plasma.Nature. 1961 Oct 14;192:180-1 PMID: 14005494
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Enzyme-like globulins from serum reproducing the vascular phenomena of inflammation. IV. Activable permeability factor and its inhibitor in the serum of the rat and the rabbit.Br J Exp Pathol. 1958 Jun;39(3):228-50 PMID: 13546545
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Activation of plasma by contact with glass: evidence for a common reaction which releases plasma kinin and initiates coagulation.J Physiol. 1958 Nov 10;144(1):1-22 PMID: 13599105
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