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PMID: 142649 Published · ppublish English Journal Article

Cytochemical localization of the K+ regulation interface between blood and brain.

Experientia ·Vol. 33 ·No. 8 ·1977-08-15 ·Pages 1093-4

Firth JA

Abstract

Phosphatase activity identified with Na+-K+-ATPase was localized at the basal surface of cerebral cortical capillary endothelium by perfusion with a p-nitrophenyl phosphate-strontium medium. The relationship of this to the blood-brain barrier to K+ is discussed.

MeSH Terms
Adenosine Triphosphatases/metabolism Animals Biological Transport, Active Blood-Brain Barrier Capillaries/enzymology Cerebral Cortex/blood supply In Vitro Techniques Male Potassium/metabolism Rats
Chemicals
Adenosine Triphosphatases Potassium
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Firth J A
References (6)
6 references, click to expand
  1. Transport ATPase cytochemistry: ultrastructural localization of potassium-dependent and potassium-independent phosphatase activities in rat kidney cortex.
    J Cell Biol. 1975 Sep;66(3):586-608 PMID: 125760
  2. Localization of ouabain-sensitive Na-K-ATPase in frog, rabbit and rat choroid plexus.
    Brain Res. 1975 Nov 28;99(1):170-4 PMID: 127406
  3. Cytological effects of salt-stress and localization of transport adenosine triphosphatase in the lateral nasal glands of the desert iguana, Dipsosaurus dorsalis.
    Anat Rec. 1974 Oct;180(2):285-97 PMID: 4278798
  4. Problems of specificity in the use of a strontium capture technique for the cytochemical localization of ouabain-sensitive, potassium-dependent phosphatase in mammalian renal tubules.
    J Histochem Cytochem. 1974 Dec;22(12):1163-8 PMID: 4140871
  5. Localization of transport adenosine triphosphatase in rat cornea.
    J Cell Biol. 1974 Mar;60(3):721-31 PMID: 4274728
  6. Junctions between intimately apposed cell membranes in the vertebrate brain.
    J Cell Biol. 1969 Mar;40(3):648-77 PMID: 5765759
Article Info
Journal
Experientia
Abbr.
Experientia
ISSN
0014-4754
DOI
10.1007/BF01945990
Published
1977-08-15
Pages
1093-4
Language
English
Region
Switzerland
NLM ID
0376547
Subset
IM
External Links
PubMed source DOI: 10.1007/BF01945990
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