MOLONEY VIRUS-INDUCED LEUKEMIAS OF MICE: MEASUREMENT IN VITRO OF SPECIFIC ANTIGEN.

Science (New York, N.Y.) ·Vol. 147 ·No. 3657 ·1965-01-29 ·Pages 506-7

HAUGHTON G

Abstract

A modified test for cytotoxic antibody may be used to measure antibody directed against the tumor-specific antigen of leukemias of mice induced by Moloney virus; cell death is detected by liberation of (51)Cr. An inhibition test based on this technique permits accurate measurement of tumor-specific antigen in cells and subcellular fractions.

Keywords

ANTIGENS CHROMIUM ISOTOPES EXPERIMENTAL LAB STUDY LEUKEMIA EXPERIMENTAL MICE ONCOGENIC VIRUSES

MeSH Terms

Animals Antibodies Antigens Antigens, Neoplasm Chromium Isotopes In Vitro Techniques Leukemia Leukemia Virus, Murine Leukemia, Experimental Mice Moloney murine leukemia virus Oncogenic Viruses Research

Chemicals

Antibodies Antigens Antigens, Neoplasm Chromium Isotopes

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

HAUGHTON G

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.147.3657.506

Published

1965-01-29

Pages

506-7

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.147.3657.506 View journal details

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MOLONEY VIRUS-INDUCED LEUKEMIAS OF MICE: MEASUREMENT IN VITRO OF SPECIFIC ANTIGEN.

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