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PMID: 1420883 Published · ppublish English Journal Article

Long tail kinetics in biophysics?

Biophysical journal ·Vol. 63 ·No. 2 ·1992-08-00 ·Pages 366-70

Nagle JF

Abstract

Long tail kinetics describe a variety of data from complex, disordered materials that cannot be described by conventional kinetics. It is suggested that the kinetics of diffusive motion in complex biological media, such as cytoplasm or biomembranes, might also have long tails. The effects of long tail kinetics are investigated for two standard biophysical measurements, fluorescence recovery after photobleaching (FRAP), and dynamic light scattering (DLS). It is shown that long tail kinetic data would yield significantly distorted and misleading results when analyzed assuming conventional kinetics.

MeSH Terms
Kinetics Mathematics Models, Biological
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Nagle J F
Department of Biological Science, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213.
References (2)
2 references, click to expand
  1. Lateral diffusion and aggregation. A Monte Carlo study.
    Biophys J. 1992 Jan;61(1):119-28 PMID: 1540685
  2. Mobility measurement by analysis of fluorescence photobleaching recovery kinetics.
    Biophys J. 1976 Sep;16(9):1055-69 PMID: 786399
Article Info
Journal
Biophysical journal
Abbr.
Biophys J
ISSN
0006-3495
Published
1992-08-00
Pages
366-70
Language
English
Region
United States
NLM ID
0370626
PMCID
PMC1262160
Subset
IM
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