ACTIVITY OF AMPICILLIN IN VITRO COMPARED WITH OTHER ANTIBIOTICS.

Journal of clinical pathology ·Vol. 17 ·1964-07-00 ·Pages 461-5

SUTHERLAND R, ROLINSON GN

Abstract

Comparative tests in vitro for antibacterial activity were carried out with ampicillin, tetracycline, and chloramphenicol using 673 clinical isolates of Gram-negative bacilli and Streptococcus faecalis. Further comparative tests were also carried out with ampicillin, chloramphenicol, colistin sulphate, colistin methane sulphonate, cycloserine, kanamycin, nitrofurantoin, polymyxin, streptomycin, and tetracycline, using groups of 20 strains of each of the main species selected at random from the total number of isolates. Of the total number of isolates a higher percentage was inhibited by ampicillin than by tetracycline or chloramphenicol. Ampicillin showed particularly high activity against certain species of bacteria and displayed an antibacterial spectrum not shown by any of the other antibiotics tested.

Keywords

ADRENAL MEDULLA AEROBACTER AEROGENES AMPICILLIN CHLORAMPHENICOL COLISTIN CYCLOSERINE ESCHERICHIA COLI EXPERIMENTAL LAB STUDY KANAMYCIN NITROFURANTOIN PHARMACOLOGY POLYMYXIN PROTEUS PSEUDOMONAS STREPTOCOCCUS FAECALIS STREPTOMYCIN TETRACYCLINE

MeSH Terms

Adrenal Medulla Ampicillin Anti-Bacterial Agents Chloramphenicol Colistin Cycloserine Enterobacter aerogenes Enterococcus faecalis Escherichia coli In Vitro Techniques Kanamycin Nitrofurantoin Pharmacology Polymyxins Proteus Pseudomonas Research Streptomycin Tetracycline

Chemicals

Anti-Bacterial Agents Polymyxins Kanamycin Chloramphenicol Ampicillin Nitrofurantoin Cycloserine Tetracycline Streptomycin Colistin

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

SUTHERLAND R

ROLINSON G N

References (12)

12 references, click to expand

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Article Info

Journal

Journal of clinical pathology

Abbr.

J Clin Pathol

ISSN

0021-9746

DOI

10.1136/jcp.17.4.461

Published

1964-07-00

Pages

461-5

Language

English

Region

England

NLM ID

0376601

PMCID

PMC480790

Subset

External Links

PubMed source DOI: 10.1136/jcp.17.4.461 PMC Full Text View journal details

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ACTIVITY OF AMPICILLIN IN VITRO COMPARED WITH OTHER ANTIBIOTICS.

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