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题目:: T helper cells.
作者:: Noelle(R),Snow(E C)
状态:: 发布时间1992-12-22 , 更新时间 2005-11-16
期刊:: Curr Opin Immunol
摘要:: B-cell proliferation and differentiation is controlled by T helper cells. Recent studies have determined that the expression of a novel, 39 kD, T-cell membrane protein is responsible for inducing T-cell-dependent B-cell activation. The receptor for this protein on the resting B cell is CD40. Once activated, B cells are induced to grow and differentiate by the elaboration of interleukin-4 and interleukin-5 from activated T cells. Together, T cell-B cell contact and soluble factors provide all the signals required for B-cell growth and differentiation.
语言:: eng
DOI:

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