IMMUNOCHEMICAL STUDIES ON THE SPECIFIC CARBOHYDRATE OF GROUP G STREPTOCOCCI.

The Journal of experimental medicine ·Vol. 119 ·1964-01-01 ·Pages 997-1003

CURTIS SN, KRAUSE RM

Abstract

Group G hemolytic streptococcal cell walls which have been treated with trypsin are composed of a group-specific polysaccharide moiety and a mucopeptide matrix. The mucopeptide contains N-acetylglucosamine, N-acetylmuramic acid, alanine, glutamic acid, lysine, and glycine, a composition similar to that of other groups of streptococci. The Group G carbohydrate is composed of rhamnose, N-acetylgalactosamine, and galactose. Serological studies suggest that the monosaccharide of L-rhamnose is a major component of the determinant of antigenic specificity.

Keywords

ALANINE ANTIGENS EXPERIMENTAL LAB STUDY GLUCOSAMINE GLUTAMATES GLYCINE HEXOSAMINES LYSINE MUCOPROTEINS PENTOSES PRECIPITIN TESTS STREPTOCOCCUS

MeSH Terms

Alanine Antigens Carbohydrates Cell Wall Galactose Glucosamine Glutamates Glycine Hexosamines Lysine Mucoproteins Pentoses Precipitin Tests Research Rhamnose Streptococcus Trypsin

Chemicals

Antigens Carbohydrates Glutamates Hexosamines Mucoproteins Pentoses Trypsin Lysine Glucosamine Alanine Rhamnose Glycine Galactose

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

CURTIS S N

KRAUSE R M

References (10)

10 references, click to expand

The lysis of group A hemolytic streptococci by extracellular enzymes of Streptomyces albus. II. Nature of the cellular substrate attacked by the lytic enzymes.
J Exp Med. 1952 Dec;96(6):569-80 PMID: 13022851
Cell-wall composition and the grouping antigens of Streptococci.
J Bacteriol. 1962 Aug;84:345-51 PMID: 13913775
Studies on L forms and protoplasts of group A streptococci. II. Chemical and immunological properties of the cell membrane.
J Exp Med. 1963 Mar 1;117:377-99 PMID: 13959531
Studies on the chemical structure of the streptococcal cell wall. I. The identification of a mucopeptide in the cell walls of groups A and A-variant streptococci.
J Exp Med. 1961 Jul 1;114:127-40 PMID: 13754097
The chemical composition of the cell wall in some gram-positive bacteria and its possible value as a taxonomic character.
J Gen Microbiol. 1956 Jul;14(3):583-600 PMID: 13346020
Studies on the chemical structure of the streptococcal cell wall. II. The composition of group C cell walls and chemical basis for serologic specificity of the carbohydrate moiety.
J Exp Med. 1962 Jan 1;115:49-62 PMID: 14459433
Variation in the group-specific carbohydrate of group A streptococci. I. Immunochemical studies on the carbohydrates of variant strains.
J Exp Med. 1955 Jul 1;102(1):11-28 PMID: 14392237
Variation in the group-specific carbohydrate of group A streptococci. II. Studies on the chemical basis for serological specificity of the carbohydrates.
J Exp Med. 1956 Nov 1;104(5):629-43 PMID: 13367334
THE SEROLOGICAL DIFFERENTIATION OF PATHOGENIC AND NON-PATHOGENIC STRAINS OF HEMOLYTIC STREPTOCOCCI FROM PARTURIENT WOMEN.
J Exp Med. 1935 Feb 28;61(3):335-49 PMID: 19870362
GROUP-SPECIFIC CARBOHYDRATE OF GROUP C-VARIANT HEMOLYTIC STREPTOCOCCI.
J Exp Med. 1963 Dec 1;118:1059-67 PMID: 14112265

Article Info

Journal

The Journal of experimental medicine

Abbr.

J Exp Med

ISSN

0022-1007

DOI

10.1084/jem.119.6.997

Published

1964-01-01

Pages

997-1003

Language

English

Region

United States

NLM ID

2985109R

PMCID

PMC2137748

Subset

External Links

PubMed source DOI: 10.1084/jem.119.6.997 PMC Full Text View journal details

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IMMUNOCHEMICAL STUDIES ON THE SPECIFIC CARBOHYDRATE OF GROUP G STREPTOCOCCI.

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