DISTRIBUTIVE PAIRING AND ANEUPLOIDY IN MAN.

Science (New York, N.Y.) ·Vol. 145 ·No. 3627 ·1964-07-03 ·Pages 66-7

GRELL RF, VALENCIA JI

Abstract

The extrapolation of the "distributive-pairing hypothesis" of meiosis in Drosophila melanogaster females to human gametogenesis is proposed to account for the co-occurrence of rare karyotype abnormalities in human families. A description of the hypothesis is presented with its application to some established cases in the cytogenetic literature.

Keywords

CHROMOSOME ABNORMALITIES DROSOPHILA EXPERIMENTAL LAB STUDY GENETICS HUMAN MONGOLISM

MeSH Terms

Aneuploidy Animals Chromosome Aberrations Cytogenetics Down Syndrome Drosophila Drosophila melanogaster Female Genetics, Medical Humans Male Meiosis Research

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

GRELL R F

VALENCIA J I

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.145.3627.66

Published

1964-07-03

Pages

66-7

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.145.3627.66 View journal details

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