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PMID: 14163958 Published · ppublish English Journal Article

FLUORESCENT ANTIBODY METHODS AND THEIR USE IN MALARIA RESEARCH.

Bulletin of the World Health Organization ·Vol. 30 ·1964-00-00 ·Pages 343-54

VOLLER A

Abstract

In the past research into malaria immunity has been hampered by the relative inefficacy of the standard serological techniques. The newer immunological tools, such as haem-agglutination, immuno-electrophoresis and fluorescent antibody testing, have proved more useful in the study of humoral immunity to malaria.The author reviews the development of immunofluorescent methods and their application to the study of malaria, and describes staining methods and the performance of the fluorescent antibody test. The test is rapid, versatile, specific and relatively simple to perform, and part of its appeal lies in the fact that the results are visually presented and can be recorded by photography.

Keywords
FLUORESCEINS FLUORESCENT ANTIBODY TECHNIC HEMAGGLUTINATION IMMUNOELECTROPHORESIS MALARIA PLASMODIUM RESEARCH
MeSH Terms
Fluoresceins Fluorescent Antibody Technique Hemagglutination Immunoelectrophoresis Malaria Plasmodium Research
Chemicals
Fluoresceins
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
VOLLER A
References (35)
35 references, click to expand
  1. THE SPECIFICITY OF TRYPANOSOMAL ANTIGENS BY IMMUNOFLUORESCENCE.
    J Gen Microbiol. 1963 Jul;32:145-9 PMID: 14045516
  2. Preserving fluorescein isocyanate for simplified preparation of fluorescent antibody.
    Science. 1957 Oct 25;126(3278):839-40 PMID: 13467285
  3. Fluorescent antibody studies with agents of varicella and herpes zoster propagated in vitro.
    Proc Soc Exp Biol Med. 1954 Aug-Sep;86(4):789-94 PMID: 13204357
  4. Fluorescent antibody studies on cross reactions between human and simian malaria in normal volunteers.
    Am J Trop Med Hyg. 1962 Sep;11:589-96 PMID: 13985215
  5. Fluorescent antibody studies on malaria parasites.
    Bull World Health Organ. 1962;27:283-7 PMID: 13997807
  6. Isothiocyanate compounds as fluorescent labeling agents for immune serum.
    Am J Pathol. 1958 Nov-Dec;34(6):1081-97 PMID: 13583098
  7. Cytochemical differentiation of Endamoeba histolytica and Endamoeba coli by means of fluorescent antibody.
    Am J Hyg. 1953 Nov;58(3):319-28 PMID: 13104391
  8. Technical factors affecting the preparation of fluorescent antibody reagents.
    J Immunol. 1961 Jul;87:72-9 PMID: 13751871
  9. DEMONSTRATION OF PASSIVE IMMUNITY IN EXPERIMENTAL MONKEY MALARIA.
    J Exp Med. 1937 Jul 31;66(2):177-90 PMID: 19870655
  10. Antigenic analysis of Entamoeba histolytica by means of fluorescent antibody. I. Instrumentation for microfluorimetry of stained amebae.
    Exp Parasitol. 1960 Feb;9:25-36 PMID: 13850705
  11. Fluorescent antibody studies on the course of antibody production and serum gamma globulin levels in normal volunteers infected with human and simian malaria.
    Am J Trop Med Hyg. 1962 Jul;11:429-36 PMID: 14460985
  12. MALARIAL ANTIBODY TITRES OF WEST AFRICANS IN BRITAIN.
    Br Med J. 1963 Aug 24;2(5355):477-9 PMID: 14043711
  13. Antibody production in human malaria as determined by the fluorescent antibody technique.
    Science. 1962 Mar 30;135(3509):1130-1 PMID: 14460984
  14. Fluorescent antibody reactions in Trypanosoma rhodesiense and T. gambiense in experimental animals.
    J Parasitol. 1963 Jun;49:380-4 PMID: 14000893
  15. Antigenic structure of Plasmodium vinckei.
    Science. 1962 Aug 17;137(3529):536-7 PMID: 14037756
  16. A new technique for the fluorescent labelling of proteins.
    Experientia. 1960 Sep 15;16:430-1 PMID: 13741735
  17. Fluorescent-antibody staining of exoerythrocytic stages of Plasmodium gallinaceum.
    Trans R Soc Trop Med Hyg. 1963 Jan;57:32-3 PMID: 13997806
  18. Malaria parasites: fluorescent antibody technique for tissue stage study.
    Science. 1963 Feb 1;139(3553):405-6 PMID: 13956538
  19. Staining toxoplasma gondii with fluorescein-labelled antibody. II. A new serologic test for antibodies to Toxoplasma based upon inhibition of specific staining.
    J Exp Med. 1957 Jun 1;105(6):557-73 PMID: 13428924
  20. Localization of antigen in tissue cells; antigens of rickettsiae and mumps virus.
    J Exp Med. 1950 Jan 1;91(1):31-8, pl PMID: 15395571
  21. Immunological studies on a fkeeze-substitution method of preparing tissue for fluorescent antibody staining.
    Immunology. 1961 Jul;4:206-18 PMID: 13686329
  22. Studies on antibody production. I. A method for the histochemical demonstration of specific antibody and its application to a study of the hyperimmune rabbit.
    J Exp Med. 1955 Jul 1;102(1):49-60 PMID: 14392240
  23. Fluorescent antisera in the detection of serological varieties of Trichomonas vaginalis.
    Br J Vener Dis. 1958 Mar;34(1):1-3 PMID: 13523189
  24. Fluorescent-antibody technic for serodiagnosis of Trypanosoma cruzi infection.
    Proc Soc Exp Biol Med. 1959 Jul;101(3):540-3 PMID: 13675310
  25. The histological localization of renin with fluorescent antibody.
    Br J Exp Pathol. 1959 Apr;40(2):155-63 PMID: 13638498
  26. Fluorescent antibody staining of human malaria parasites.
    Exp Parasitol. 1961 Sep;11:128-32 PMID: 13921464
  27. Staining Toxoplasma gondii with fluorescein-labelled antibody. I. The reaction in smears of peritoneal exudate.
    J Exp Med. 1957 Jun 1;105(6):549-56 PMID: 13428923
  28. Fluorescent protein tracers; a trial of new fluorochromes and the development of an alternative to fluorescein.
    Immunology. 1958 Oct;1(4):315-27 PMID: 13610415
  29. Gamma-globulin and acquired immunity to human malaria.
    Nature. 1961 Nov 25;192:733-7 PMID: 13880318
  30. A comparison of fluorescein and I 131 as labels for determining the in vivo localization of anti-tissue antibodies.
    Int Arch Allergy Appl Immunol. 1958;12(3-4):125-36 PMID: 13574920
  31. Staining of complement and modification of fluorescent antibody procedures.
    J Immunol. 1958 Feb;80(2):122-31 PMID: 13514081
  32. Localization of adrenocorticotropic hormone by histochemical and immunochemical methods.
    J Exp Med. 1951 Jul 1;94(1):21-30 PMID: 14850633
  33. Rapid separation of fluorescent antisera and uncojugated dye.
    Acta Histochem. 1961 Jun 26;11:306-8 PMID: 13789012
  34. Fluorescent antibody staining as a measure of malarial antibody.
    Proc Soc Exp Biol Med. 1962 Aug-Sep;110:907-10 PMID: 13926639
  35. A LONGITUDINAL LONGITUDINAL SURVEY OF NATURAL MALARIA INFECTION IN A GROUP OF WEST AFRICAN ADULTS. I.
    West Afr Med J. 1963 Aug;12:141-73 PMID: 14052649
Article Info
Journal
Bulletin of the World Health Organization
Abbr.
Bull World Health Organ
ISSN
0042-9686
Published
1964-00-00
Pages
343-54
Language
English
Region
Switzerland
NLM ID
7507052
PMCID
PMC2554825
Subset
OM
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