NUCLEIC ACID METABOLISM IN L CELLS INFECTED WITH A MEMBER OF THE PSITTACOSIS GROUP.

Science (New York, N.Y.) ·Vol. 145 ·No. 3634 ·1964-08-21 ·Pages 819-21

SCHECHTER EM, TRIBBY II, MOULDER JW

Abstract

Multiplication of the meningopneumonitis agent in the cytoplasm of L cells in suspension culture is accompanied by parallel increases in cytoplasmic DNA, RNA, and phospholipid. Synthesis of RNA and phospholipid in infected cells is inhibited at the height of meningopneumonitis multiplication, but nuclear DNA synthesis is inhibited earlier and to a greater degree

Keywords

DNA VIRAL EXPERIMENTAL LAB STUDY LIPID METABOLISM METABOLISM MICE MIYAGAWANELLA PHOSPHOLIPIDS PHOSPHORUS ISOTOPES RADIOAUTOGRAPHY RNA VIRAL TISSUE CULTURE VIRUS CULTIVATION

MeSH Terms

Autoradiography Chlamydophila psittaci Cytoplasm DNA DNA, Viral Lipid Metabolism Metabolism Mice Phospholipids Phosphorus Isotopes Psittacosis RNA RNA, Viral Research Tissue Culture Techniques Virus Cultivation

Chemicals

DNA, Viral Phospholipids Phosphorus Isotopes RNA, Viral RNA DNA

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

SCHECHTER E M

TRIBBY I I

MOULDER J W

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.145.3634.819

Published

1964-08-21

Pages

819-21

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.145.3634.819 View journal details

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