DENSITY GRADIENT CENTRIFUGATION OF A MURINE LEUKEMIA VIRUS.

Science (New York, N.Y.) ·Vol. 144 ·No. 3622 ·1964-05-29 ·Pages 1144-7

O'CONNOR TE, RAUSCHER FJ, ZEIGEL RF

Abstract

The Rauscher leukemia virus separated as a single band upon density gradient centrifugation in cesium chloride, rubidium chloride, sucrose, potassium citrate, or potassium tartrate. Prolonged exposure to concentrated potassium citrate or potassium tartrate solutions caused lysis of the virus; the resulting products, having different densities, separated on the density gradients.

Keywords

CENTRIFUGATION CITRATES EXPERIMENTAL LAB STUDY ONCOGENIC VIRUSES PHARMACOLOGY POTASSIUM TARTRATES VIRUS CULTIVATION

MeSH Terms

Animals Centrifugation Centrifugation, Density Gradient Cesium Chlorides Citrates Leukemia Virus, Murine Mice Oncogenic Viruses Pharmacology Potassium Research Rubidium Sucrose Tartrates Virus Cultivation Viruses

Chemicals

Chlorides Citrates Tartrates Cesium Sucrose cesium chloride Rubidium rubidium chloride Potassium tartaric acid

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

O'CONNOR T E

RAUSCHER F J

ZEIGEL R F

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.144.3622.1144

Published

1964-05-29

Pages

1144-7

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.144.3622.1144 View journal details

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