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PMID: 14107432 Published · ppublish English Journal Article

CEREBELLAR ATAXIA IN HAMSTERS INOCULATED WITH RAT VIRUS.

Science (New York, N.Y.) ·Vol. 143 ·No. 3610 ·1964-03-06 ·Pages 1047-8

KILHAM L, MARGOLIS G

Abstract

Chronic ataxia associated with hypoplasia of the cerebellum was induced by intracerebral inoculation of newborn hamsters with various strains of rat virus. The condition usually became recognizable within 3 weeks of inoculation and remained static as the animals matured. Preliminary studies suggest that hypoplasia is induced by the rat virus acting on the outer germinal layer of the cerebellum at a critical time in its ontogenic development.

Keywords
ANIMALS NEWBORN ATAXIA CEREBELLAR DISEASES EXPERIMENTAL LAB STUDY HAMSTERS PATHOLOGY VERTEBRATE VIRUSES
MeSH Terms
Animals Animals, Newborn Ataxia Cerebellar Ataxia Cerebellar Diseases Cerebellum Cricetinae Parvovirus Pathology Research Vertebrates Viruses
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
KILHAM L
MARGOLIS G
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
Published
1964-03-06
Pages
1047-8
Language
English
Region
United States
NLM ID
0404511
Subset
OM
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