WASTING DISEASE INDUCED IN YOUNG MICE BY ADMINISTRATION OF CORTISOL ACETATE.

Science (New York, N.Y.) ·Vol. 143 ·No. 3609 ·1964-02-28 ·Pages 965-6

SCHLESINGER M, MARK R

Abstract

A single injection of cortisol acetate into young mice induced a wasting syndrome similar to that observed in runt disease and in the post-thymectomy syndrome. The course of the disease was less severe if the dose of the drug was decreased or if the animals were older at the time of injection.

Keywords

CACHEXIA EXPERIMENTAL LAB STUDY HYDROCORTISONE TOXICOLOGY METABOLIC DISEASES MICE TOXICOLOGIC REPORT

MeSH Terms

Acetates Animals Cachexia Graft vs Host Disease Hydrocortisone/toxicity Metabolic Diseases Mice Research Toxicology Wasting Syndrome

Chemicals

Acetates hydrocortisone acetate Hydrocortisone

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

SCHLESINGER M

MARK R

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.143.3609.965

Published

1964-02-28

Pages

965-6

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.143.3609.965 View journal details

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WASTING DISEASE INDUCED IN YOUNG MICE BY ADMINISTRATION OF CORTISOL ACETATE.

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