STUDIES ON NORMAL AND LEUKEMIC LEUKOCYTES. VI. THYMIDYLATE SYNTHETASE AND DEOXYCYTIDYLATE DEAMINASE.

The Journal of clinical investigation ·Vol. 42 ·1963-12-00 ·Pages 1913-21

SILBER R, GABRIO BW, HUENNEKENS FM

Abstract

暂无摘要

Keywords

ADENOSINE TRIPHOSPHATE AMINOHYDROLASES CARBON ISOTOPES CHROMATOGRAPHY ENZYME INHIBITORS ENZYME TESTS FLUORODEOXYURIDINE LEUKEMIA LEUKEMIA LYMPHOCYTIC LEUKEMIA MYELOCYTIC LEUKOCYTES LIGASES NUCLEOTIDES SPECTROPHOTOMETRY

MeSH Terms

Adenosine Triphosphate Aminohydrolases Carbon Isotopes Chromatography Clinical Enzyme Tests DCMP Deaminase Enzyme Inhibitors Floxuridine Leukemia Leukemia, Lymphoid Leukemia, Myeloid Leukocytes Ligases Lymphocytes Nucleotides Spectrophotometry Thymidylate Synthase

Chemicals

Carbon Isotopes Enzyme Inhibitors Nucleotides Floxuridine Adenosine Triphosphate Thymidylate Synthase Aminohydrolases DCMP Deaminase Ligases

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

SILBER R

GABRIO B W

HUENNEKENS F M

References (17)

17 references, click to expand

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Metabolism of human leukocytes in vitro. I. Effects of A-methopterin on formate-C14 incorporation.
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Proliferative capacity of acute leukaemia cells.
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Leukemic cell proliferation as determined by in vitro deoxyribonucleic acid synthesis.
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The enzymatic synthesis of thymidylate. I. Early steps in the purification of thymidylate synthetase of Escherichia coli.
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Biochemical changes during treatment with 5-fluorouracil.
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The biosynthesis of thymidylic acid. III. Purification of thymidylate synthetase and its spectrophotometric assay.
J Biol Chem. 1962 Mar;237:812-8 PMID: 13869774
Thymidine phosphorylation and deoxyribonucleic acid synthesis in human leukaemic cells.
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Human leukocyte metabolism in vitro. I. Incorporation of adenine-8-C-14 and formate-C-14 into the nucleic acids of leukemic leukocytes.
J Clin Invest. 1962 Jan;41:67-79 PMID: 13909938
STUDIES ON NORMAL AND LEUKEMIC LEUKOCYTES. IV. TETRAHYDROFOLATE-DEPENDENT ENZYME SYSTEMS AND DIHYDROFOLIC REDUCTASE.
J Clin Invest. 1963 Dec;42:1899-907 PMID: 14090749
Nucleotide interconversions in embryonic and neoplastic tissues. I. The conversion of deoxycytidylic acid to deoxyuridylic acid and thymidylic acid.
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Article Info

Journal

The Journal of clinical investigation

Abbr.

J Clin Invest

ISSN

0021-9738

DOI

10.1172/JCI104877

Published

1963-12-00

Pages

1913-21

Language

English

Region

United States

NLM ID

7802877

PMCID

PMC289479

Subset

External Links

PubMed source DOI: 10.1172/JCI104877 PMC Full Text View journal details

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STUDIES ON NORMAL AND LEUKEMIC LEUKOCYTES. VI. THYMIDYLATE SYNTHETASE AND DEOXYCYTIDYLATE DEAMINASE.

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