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PMID: 14060448 Published · ppublish English Journal Article

POST-TETANIC REPETITIVE ACTIVITY IN THE CAT SOLEUS NERVE. ITS ORIGIN, COURSE, AND MECHANISM OF GENERATION.

The Journal of general physiology ·Vol. 47 ·1963-09-00 ·Pages 53-70

STANDAERT FG

Abstract

Subsequent to conditioning by a high frequency stimulus axons of the cat soleus nerve respond to single stimuli with brief trains of repetitive action potentials. This phenomenon, post-tetanic repetitive activity (PTR), was studied in individual axons and single motor units of an in situ cat soleus nerve-muscle preparation. The occurrence, intensity, and duration of PTR are principally dependent on the frequency and duration of the conditioning tetanus. PTR occurs synchronously in the axon and muscles of single motor units. An analysis of the temporal relationships of the repetitive nerve and muscle potentials showed that PTR is generated in the motor nerve terminal. It is postulated that PTR is produced by a generator potential which is developed in the post-tetanic period between the unmyelinated nerve terminal and the last node of Ranvier.

Keywords
CATS EXPERIMENTAL LAB STUDY NEUROMUSCULAR JUNCTION PERIPHERAL NERVES PHYSIOLOGY
MeSH Terms
Action Potentials Cats Muscle Contraction Muscle, Skeletal Muscles Neuromuscular Junction Peripheral Nerves Physiology Research
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
STANDAERT F G
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26 references, click to expand
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Article Info
Journal
The Journal of general physiology
Abbr.
J Gen Physiol
ISSN
0022-1295
DOI
10.1085/jgp.47.1.53
Published
1963-09-00
Pages
53-70
Language
English
Region
United States
NLM ID
2985110R
PMCID
PMC2195323
Subset
OM
External Links
PubMed source DOI: 10.1085/jgp.47.1.53 PMC Full Text View journal details
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