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PMID: 140460 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Lymphocyte and fibroblast chalones: some chemical properties.

Science (New York, N.Y.) ·Vol. 196 ·No. 4292 ·1977-05-20 ·Pages 896-7

Houck JC, Kanagalingam K, Hunt C, Attallah A, Chung A

Abstract

Experiments with lymphocyte and fibroblast chalones indicate that they are complexed strongly with RNA in tissue extracts; have a molecular weight of less than 10,000 and more than 1,000 daltons, and probably about 5,000 daltons; are strongly cationically charged; and contain mannose and perhaps other carbohydrates.

MeSH Terms

Cell Division/drug effects Cells, Cultured Fibroblasts/drug effects Glycopeptides/analysis Growth Inhibitors/isolation & purification,pharmacology Isoelectric Point Lymphocytes/drug effects Mannose/analysis Molecular Weight RNA/metabolism

Chemicals

Glycopeptides Growth Inhibitors RNA Mannose

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Houck J C

Kanagalingam K

Hunt C

Attallah A

Chung A

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.140460

Published

1977-05-20

Pages

896-7

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.140460 View journal details

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