Action of sympathomimetic drugs on the isolated junction of the bile duct and duodenum.

British journal of pharmacology and chemotherapy ·Vol. 20 ·1963-04-00 ·Pages 221-9

CREMA A, BERTE F

Abstract

The actions of adrenaline, noradrenaline and phenylephrine were studied both on the terminal tract of bile duct (prepared as spiral strips or intact) and on the adjacent duodenum taken from the calf and the cat. These amines contract the terminal bile duct and relax the duodenum. Furthermore, on the basis of the action of some adrenaline antagonists, the hypothesis is advanced that there are alpha-receptors which mediate contraction of muscle in the sphincterial zone of the bile duct.

Keywords

BILE DUCTS DUODENUM EPINEPHRINE NOREPINEPHRINE PHENYLEPHRINE

MeSH Terms

Animals Bile Ducts Cats Duodenum Epinephrine Norepinephrine Phenylephrine Sympathomimetics

Chemicals

Sympathomimetics Phenylephrine Norepinephrine Epinephrine

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

CREMA A

BERTE F

References (13)

13 references, click to expand

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Article Info

Journal

British journal of pharmacology and chemotherapy

Abbr.

Br J Pharmacol Chemother

ISSN

0366-0826

DOI

10.1111/j.1476-5381.1963.tb01461.x

Published

1963-04-00

Pages

221-9

Language

English

Region

England

NLM ID

0154627

PMCID

PMC1703626

Subset

External Links

PubMed source DOI: 10.1111/j.1476-5381.1963.tb01461.x PMC Full Text

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Action of sympathomimetic drugs on the isolated junction of the bile duct and duodenum.

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