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PMID: 1382134 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Atomic force microscopy of conventional and unconventional nucleic acid structures.

Journal of microscopy ·Vol. 167 ·No. Pt 1 ·1992-07-00 ·Pages 77-84

Henderson E

Abstract

Images of conventional (Watson-Crick base paired) and unconventional (G4 RNA) nucleic acid structures have been obtained by atomic force microscopy. The images are reproducibly generated from samples deposited on freshly cleaved mica. Periodic substructural features are evident in fibres observed in both cases. In the case of G4 RNA, tip-induced formation of large fibres is observed.

MeSH Terms

DNA/ultrastructure Guanine Nucleotides/chemistry Microscopy, Scanning Tunneling/methods RNA/ultrastructure

Chemicals

Guanine Nucleotides RNA DNA

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Henderson E

Department of Zoology and Genetics, Iowa State University, Ames 50011.

Article Info

Journal

Journal of microscopy

Abbr.

J Microsc

ISSN

0022-2720

DOI

10.1111/j.1365-2818.1992.tb03220.x

Published

1992-07-00

Pages

77-84

Language

English

Region

England

NLM ID

0204522

Subset

Grants

NIGMS NIH HHS · GM41023-01A1 · United States

External Links

PubMed source DOI: 10.1111/j.1365-2818.1992.tb03220.x View journal details

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Atomic force microscopy of conventional and unconventional nucleic acid structures.

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