Simultaneous production of two capsular polysaccharides by pneumococcus. I. Properties of a pneumococcus manifesting binary capsulation.

The Journal of experimental medicine ·Vol. 110 ·1959-10-01 ·Pages 571-84

AUSTRIAN R, BERNHEIMER HP

Abstract

Pneumococci manifesting binary capsulation have been produced through the agency of transformation reactions. Such cells produce two capsular polysaccharides which are closely similar if not identical with those produced by corresponding singly capsulated strains. Binary capsulation in pneumococcus provides a new basis for serologic cross-reactivity in this species.

Keywords

DIPLOCOCCUS PNEUMONIAE/metabolism POLYSACCHARIDES/metabolism

MeSH Terms

Cross Reactions Polysaccharides/metabolism Streptococcus pneumoniae/metabolism

Chemicals

Polysaccharides

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

AUSTRIAN R

BERNHEIMER H P

References (7)

7 references, click to expand

The use of precipitin analysis in agar for the study of human streptococcal infections. II. Ouchterlony and Oakley technics.
J Exp Med. 1955 May 1;101(5):557-76 PMID: 14367679
Morphologic variation in pneumococcus. I. An analysis of the bases for morphologic variation in pneumococcus and description of a hitherto undefined morphologic variant.
J Exp Med. 1953 Jul;98(1):21-34 PMID: 13069647
STUDIES ON IMMUNOLOGICAL RELATIONSHIPS AMONG THE PNEUMOCOCCI : II. A COMPARISON OF THE ANTIBODY RESPONSES OF MICE AND OF RABBITS TO IMMUNIZATION WITH TYPICAL TYPE III PNEUMOCOCCI AND TO IMMUNIZATION WITH A RELATED STRAIN.
J Exp Med. 1928 May 31;47(6):933-43 PMID: 19869455
Additive effects of certain transforming agents from some variants of pneumococcus.
J Exp Med. 1949 Apr 1;89(4):399-424 PMID: 18113913
STEPWISE INTRATYPE TRANSFORMATION OF PNEUMOCOCCUS FROM R TO S BY WAY OF A VARIANT INTERMEDIATE IN CAPSULAR POLYSACCHARIDE PRODUCTION.
J Exp Med. 1947 Nov 30;86(6):439-52 PMID: 19871689
In vitro production of new types of hemophilus influenzae.
J Exp Med. 1953 Apr;97(4):467-82 PMID: 13052813
STUDIES ON IMMUNOLOGICAL RELATIONSHIPS AMONG THE PNEUMOCOCCI : I. A VIRULENT STRAIN OF PNEUMOCOCCUS WHICH Is IMMUNOLOGICALLY RELATED TO, BUT NOT IDENTICAL WITH TYPICAL STRAINS OF TYPE III PNEUMOCOCCI.
J Exp Med. 1928 May 31;47(6):917-31 PMID: 19869454

Article Info

Journal

The Journal of experimental medicine

Abbr.

J Exp Med

ISSN

0022-1007

DOI

10.1084/jem.110.4.571

Published

1959-10-01

Pages

571-84

Language

English

Region

United States

NLM ID

2985109R

PMCID

PMC2137005

Subset

External Links

PubMed source DOI: 10.1084/jem.110.4.571 PMC Full Text View journal details

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Simultaneous production of two capsular polysaccharides by pneumococcus. I. Properties of a pneumococcus manifesting binary capsulation.

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